Jaguars vs. Bengals: TNF odds market update

Week 4's Thursday Night Football matchup between the Jacksonville Jaguars and Cincinnati Bengals will represent a battle of No. 1 overall draft picks and a rematch of quarterbacks who last squared off in the 2019 College Football Playoff National Championship.

This year's top draft pick, Trevor Lawrence, experienced his first collegiate loss in that title game, where 2020 No. 1 draft pick Joe Burrow and his LSU Tigers bested Clemson.

Lawrence lost just one more game in college, but the start to his NFL career has been a far different story.

The rookie is 0-3 under new head coach Urban Meyer and is one defeat away from tying the total losses he suffered in high school and college.

Burrow, on the other hand, has guided Cincinnati to a 2-1 record, with victories over Minnesota and AFC North rival Pittsburgh.

His Bengals are a 7.5-point home favorite in Thursday night's matchup.

Let's find out how the public is betting the moneyline, point spread, totals, and more at TwinSpires Sports, ahead of the Jaguars vs. Bengals on Thursday Night Football.

Moneyline bettors are confident Cincinnati (-345 odds) will get its third win of the season and for good reason.

You have to go back more than a year, to Week 1 of the 2020 season, to find the last time the Jaguars celebrated a victory.

Since then, the franchise has suffered defeat in 18 straight and is just two losses away from becoming the third team in NFL history to lose 20 consecutive games.

Jacksonville has lost all three of its matchups this season by an average margin of 12.7 points. 

Turnovers have been a major issue. The team ranks last in turnover differential (-8), and Lawrence has accounted for all nine of the Jaguars' giveaways (seven interceptions and two lost fumbles).

Spread bettors are also high on the Bengals to cover as 7.5-point home favorites.

Dating back to 2011, the Bengals own a 3-2 series lead over the Jaguars and last won by eight points, in a 33-25 home victory in 2020.

This season, Cincinnati is 2-1 against the spread, while Jacksonville has failed to cover in three games.

The Bengals are 4-1 ATS in their last five Thursday games and 5-2 ATS in their last seven home games.

The favorite is 3-0-1 ATS in the last four meetings between Cincinnati and Jacksonville.

The public is more evenly split on Thursday's points total, which is set at 46.

More than 70% of the handle is backing the Under, whereas 67% of all tickets placed are in favor of the Over.

The Bengals defense ranks sixth in points surrendered (18 per game) and held Pittsburgh to just 10 in a Week 3 road win.

The Jags have scored just 17.7 points per game and allow 30.3 points per contest (fifth worst in the league). 

The Under is 5-2-1 in the Bengals’ last eight games.

Most popular prop bet: Ja’Marr Chase to score first touchdown

The most popular prop wager for Thursday's matchup is Ja'Marr Chase to score the first touchdown (+700).

Burrow's former LSU teammate has already recorded four receiving touchdowns through his first three games and is the youngest player (21) to do so.

In last week's win against the Steelers, the rookie also became the only player in the Super Bowl era to post a 30-yard touchdown reception in each of his first three games.

Chase currently leads the Bengals in receiving yards (220), touchdowns (four), and yards per catch (20).

The deep threat is a prime candidate to reach the end zone against the Jaguars defense, which ranks 28th against the pass and has given up two receiving touchdowns in two of three games.